Connecticut, Delaware, Maryland, Pennsylvania and Rhode Island hold elections on 26 April in a series of polls known as the "Acela Primary" - after the rail service which links all five states.
Republican frontrunner Donald Trump will seek to build on his big win in New York and further dent the hopes of Ted Cruz, who has formed a pact with John Kasich in a last-ditch effort to block Mr Trump's path to the nomination.
Hillary Clinton is hoping to deliver a knockout blow to challenger Bernie Sanders.
Results state by state
Click or tap on the links below for full results, provided by the Associated Press.
The delegate tracker
Winning delegates, the people who endorse a candidate at the party conventions in July, is key to securing the nomination.
The Democratic totals include the delegates won per state, as well as so-called "unpledged" or "super delegates". Hillary Clinton has a huge lead among the party leaders and elected officials who each get a vote at the convention.
AP conducts surveys of these super delegates, and adds them to a candidate's totals if they indicate their support. But super delegates can - and do - change their minds during the course of the campaign, so the figures may shift as the race unfolds.
The delegate tracker is updated automatically. There may be a short delay between the delegates being assigned and the totals changing.
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